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Basic immunology abbas outline skin#
Intraepithelial lymphocytes present in the skin.Epithelial barrier function of the skin of her foot.All of the following are mechanisms of innate immunity that may be protecting the patient against pathogenic microbes in the heel wound EXCEPT: Two days later, she is taken to the pediatrician because her heel is painful, red, and swollen and is warm to the touch.
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A 4-year-old girl stepped on a rusty nail in her backyard.Although it provides the initial, rapid response against microbes, innate immunity can influence adaptive immune responses to tailor them against particular microbes. It is also true that, like the adaptive response, the innate immune response consists of recognition, activation, and effector phases. Studies have shown that hampering effector mechanisms of innate immunity renders hosts much more susceptible to infection, even with a functional adaptive immune system. Innate immunity is the phylogenetically oldest mechanism of microbial defense, and it is present in all multicellular organisms, including plants and insects. Adaptive immunity, being more potent and specialized, plays a critical role in defending against these virulent microbes. Innate immunity is the first line of defense against infections, yet many pathogenic microbes have evolved strategies to resist innate immunity. The innate immune response against microbes influences the type of adaptive immune response that develops.The innate immune response can be divided into recognition, activation, and effector phases.
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Innate immunity is better suited for eliminating virulent, resistant microbes than is adaptive immunity.Deficiencies in innate immunity markedly increase host susceptibility to infection, even in the setting of an intact adaptive immune response.Innate immunity is present in all multicellular organisms, including plants and insects.Which of the following statements about the innate immune system is NOT true?.Basic Immunology Functions And Disorders of the Immune System 4th Edition by Abul K.